Review

Bringing pharmacomicrobiomics to the clinic through well-designed studies

Pharmacomicrobiomic studies investigate drug-microbiome interactions, such as the effect of microbial variation on drug response and disposition. Studying and understanding the interactions between the gut microbiome and drugs is becoming …

Role of the Gut Microbiome in Cardiovascular Drug Response: The Potential for Clinical Application

Response to cardiovascular drugs can vary greatly between individuals, and the role of the microbiome in this variability is being increasingly appreciated. Recent evidence indicates that bacteria and other microbes are responsible for direct and …

Elucidation of Cellular Contributions to Heparin-Induced Thrombocytopenia Using Omic Approaches

Heparin-induced thrombocytopenia (HIT) is an unpredictable, complex, immune-mediated adverse drug reaction associated with a high mortality. Despite decades of research into HIT, fundamental knowledge gaps persist regarding HIT likely due to the …