research

Local Ancestry‐Informed Candidate Pathway Analysis of Warfarin Stable Dose in Latino Populations

So excited to see this publication finally come out. This was my first project I worked on with the Karnes Lab and I really think it became a diamond from the rough.

Local Ancestry‐Informed Candidate Pathway Analysis of Warfarin Stable Dose in Latino Populations

Accuracy of warfarin dose prediction algorithms may be improved by including data from diverse populations in genetic studies of dose variability. Here, we surveyed single nucleotide polymorphisms in vitamin K-related genetic pathways for association …

Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia

Heparin, a widely used anticoagulant, carries the risk of an antibody-mediated adverse drug reaction, heparin-induced thrombocytopenia (HIT). A subset of heparin-treated patients produces detectable levels of antibodies against complexes of heparin …

ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is an unpredictable, potentially catastrophic adverse effect resulting from an immune response to platelet factor 4 (PF4)/heparin complexes. We performed a genome-wide association study (GWAS) with positive …

ASCPT Presidential Trainee 2021

I’ve been MIA! Grad school is exhausting! Alas, it’s summer 2021 and I’m back to update my site with some w’s! American Society of Clinical Pharmacology and Therapeutics Annual Meeting I presented my work on warfarin stable dose prediction in a diverse population featuring a large proportion of Hispanic/Latino reporting warfarin users at the ASCPT 2021 Annual Meeting (,virtually).

PGRN Annual Meeting 2020

Pharmacogenomics Global Research Network (Actually this name is brand new, like yesterday. So in October, when this meeting occurred, the PGRN was still the PharmacoGenomics Research Network). I presented a poster at the PGRN Annual Meeting in October 2020.